Braun Lab 2019

  • Set1/COMPASS repels heterochromatin invasion at euchromatic sites by disrupting Suv39/Clr4 activity and nucleosome stability.
    Greenstein RA, Barrales RR, Sanchez NA, Bisanz JE, Braun S, Al-Sady B
    Genes Dev. 2019 Dec 5. doi: 10.1101/gad.328468.119.
  • Neutral epigenetic inheritance: being prepared for future generations.
    Capella M and Braun S
    Nat Struct Mol Biol. 2019 May 20. doi: 10.1038/s41594-019-0239-5.
  • TASks for subtelomeres: when nucleosome loss and genome instability are favored.
    van Emden TS and Braun S
    Curr Genet. 2019 May 7. doi: 10.1007/s00294-019-00986-8.
  • Shelterin and subtelomeric DNA sequences control nucleosome maintenance and genome stability.
    van Emden TS*, Forn M*, Forné I, Sarkadi Z, Capella M, Martín Caballero L, Fischer-Burkart S,  Brönner C, Simonetta M, Toczyski D, Halic M, Imhof A, and Braun S
    EMBO Rep. 2019 Jan;20(1). pii: e47181. doi: 10.15252/embr.201847181
    *co-first authors
  • The fission yeast nucleoporin Alm1 is required for proteasomal degradation of kinetochore components.
    Salas-Pino S, Gallardo P, Barrales RR, Braun S, Daga RR.
    J Cell Biol. 2017 Oct 3. pii: jcb.201612194. doi: 10.1083/jcb.201612194.
  • The histone acetyltransferase Mst2 protects active chromatin from epigenetic silencing by acetylating the ubiquitin ligase Brl1.
    Flury V, Georgescu PR, Iesmantavicius V, Shimada Y, Kuzdere T, Braun S*, and Bühler M*
    Mol. Cell. 2017 Jul 20;67(2):294-307.e9.
    doi: 10.1016/j.molcel.2017.05.026. Epub 2017 Jun 22. *corresponding authors
  • Beyond Tethering and the LEM domain: MSCellaneous functions of the inner nuclear membrane Lem2.
    Braun S*, Barrales RR.
    Nucleus. 2016 Nov;7(6):523-531 doi: 10.1080/19491034.2016.1252892.
    *corresponding author
  • Chromatin binding and silencing: Two roles of the same protein Lem2.
    Barrales RR , Braun S.
    Microb Cell. 2016 Apr 4;3(4):185-188 doi: 10.15698/mic2016.04.495.
  • Sensitive and Quantitative Three-Color Protein Imaging in Fission Yeast Using Spectrally Diverse, Recoded Fluorescent Proteins with Experimentally-Characterized In Vivo Maturation Kinetics.
    Al-Sady B, Greenstein RA, El-Samad HJ, Braun S, Madhani HD.
    PLoS One. 2016 Aug 1;11(8):e0159292.
  • Control of heterochromatin localization and silencing by the nuclear membrane protein Lem2.
    Barrales RRForn MGeorgescu PRSarkadi Z, and Braun S.
    Genes Dev. 2016 Jan 15;30(2):133-48.. doi: 10.1101/gad.271288.115
  • Global regulation of heterochromatin spreading by Leo1.
    Verrier L, Taglini F, Barrales RR, Webb S, Urano T, Braun S, and Bayne EH.
    Open Biol. 2015 May;5(5): pii: 150045. doi: 10.1098/rsob.150045.
  • Almouzni G, Altucci, L, Amati B, Ashley N, Baulcombe D, Beaujean N, Bock C, Bongcam-Rudloff E, Bousquet J, Braun S et al. (2014). Relationship between genome and epigenome—challenges and requirements for future research. BMC Genomics;15(487):1-7.
  • Shaping the landscape: mechanistic consequences of ubiquitin modification of chromatin.
    Braun S*  and Madhani HD.
    EMBO Rep. 2012 Dec;13(12):1152. doi: 10.1038/embor.2012.78. *corresponding author


  • Ers1 links HP1 to RNAi.
    Rougemaille M, Braun S, Coyle S, Dumesic PA, Garcia JF, Isaac RS, Libri D, Narlikar GJ, Madhani HD.
    Proc Natl Acad Sci U S A. 2012 Jun 25. [Epub ahead of print] PubMed
  • The ubiquitin ligase Cul4-Ddb1Cdt2 inhibits the invasion of a boundary-associated anti-silencing factor into heterochromatin.
    Braun S, Garcia JF, Rowley M, Rougemaille M, Shankar S, Madhani HD (2011).
    Cell 144(1):41-54.
  • Ers1, a rapidly diverging protein essential for RNA interference-dependent heterochromatic silencing in Schizosaccharomyces pombe. Rougemaille M, Shankar S, Braun S, Rowley M, Madhani HD (2008).
    J Biol Chem. 283(38):25770-3.
  • A comprehensive strategy enabling high-resolution functional analysis of the yeast genome.
    Breslow DK, Cameron DM, Collins SR, Schuldiner M, Stewart-Ornstein J, Newman HW, Braun S, Madhani HD, Krogan NJ, Weissman JS (2008). Nat Methods. 5(8):711-8.
  • SM-protein-controlled ER-associated degradation discriminates between different SNAREs.
    Braun S, Jentsch S. (2007).
    EMBO Rep. 8(12):1176-82.
  • A Series of Ubiquitin-Binding Factors Connects Cdc48/p97 to Substrate Multiubiquitylation and Proteasomal Targeting.
    Richly H, Rape M, Braun S, Rumpf S, Hoege C and Jentsch S (2005).
    Cell 120(1):73-84.
  • Role of the Ubiquitin-selective Cdc48Ufd1-Npl4 chaperone (segregase) in ERAD of Ole1 and other substrates.
    Braun S, Matuschweski K, Rape M, Thoms S and Jentsch S (2002).
    EMBO J 21, 614-621.
  • Dexamethasone-enhanced sensitivity of mouse hippocampal HT22 cells for oxidative stress is associated with the suppression of nuclear factor-kappaB.
    Braun S, Liebetrau W, Berning B, Behl C (2000).
    Neurosci Letters 295:101-4.
  • Glutathione and a UV light-induced glutathione S-transferase are involved in signaling to chalcone synthase in cell cultures.
    Loyall L, Uchida K, Braun S, Furuya M, Frohnmeyer H (2000).
    Plant Cell 12:1939-50.

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